Protein data bank

protein data bank

What is the Protein Data Bank (PDB)?

The Protein Data Bank (PDB) is the single global archive of experimentally determined three-dimensional (3D) structure data of biological macromolecules. Since 2003, the PDB has been managed by the Worldwide Protein Data Bank (wwPDB; wwpdb.org), an international consortium that collaboratively overs …

What is the Protein Data database?

The Protein database is a collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB. Protein sequences are the fundamental determinants of biological structure and function.

What is the RCSB protein data bank?

This resource is powered by the Protein Data Bank archive-information about the 3D shapes of proteins, nucleic acids, and complex assemblies that helps students and researchers understand all aspects of biomedicine and agriculture, from protein synthesis to health and disease. As a member of the wwPDB, the RCSB PDB curates and annotates PDB data.

Where is the data stored in the PDB?

The data of such structures is stored on the electron density server. Historically, the number of structures in the PDB has grown at an approximately exponential rate, with 100 registered structures in 1982, 1,000 structures in 1993, 10,000 in 1999, and 100,000 in 2014. The file format initially used by the PDB was called the PDB file format.

What is the Protein Data Bank?

The Protein Data Bank (PDB) was established as the 1 st open access digital data resource in all of biology and medicine ( Historical Timeline ). It is today a leading global resource for experimental data central to scientific discovery.

What is the RCSB PDB?

The Vision of the RCSB PDB is to enable open access to the accumulating knowledge of 3D structure, function, and evolution of biological macromolecules, expanding the frontiers of fundamental biology, biomedicine, and biotechnology.

Which databases use protein structures deposited in PDB?

Many other databases use protein structures deposited in the PDB. For example, SCOP and CATH classify protein structures, while PDBsum provides a graphic overview of PDB entries using information from other sources, such as Gene ontology.

What is the Protein Data Book (PDB)?

Two forces converged to initiate the PDB: a small but growing collection of sets of protein structure data determined by X-ray diffraction; and the newly available (1968) molecular graphics display, the Brookhaven RAster Display (BRAD), to visualize these protein structures in 3-D.

Postagens relacionadas: